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KMID : 0359320130530010001
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Korean Journal of Veterinary Research
2013 Volume.53 No. 1 p.1 ~ p.5
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Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran
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Rassouli Maryam
Razmi Golam Reza
Movassaghi Ahmad Reza
Bassami Mohammad Reza
Sami Mehrdad
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Abstract
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The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs such as brain, liver, heart, lung, kidney, spleen) (4.6~14.4% with 95% CI) were positive in IHC with a very good logical agreement among different diagnostic techniques (κ = 0.73, 0.8) and with no significant difference among different fetal age groups (p > 0.05).
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KEYWORD
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histopathology, immunohistochemistry, Iran, ovine abortion, Toxoplasma gondii
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